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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIPK4
All Species:
22.73
Human Site:
S423
Identified Species:
50
UniProt:
P57078
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57078
NP_065690
832
91611
S423
G
K
R
L
S
G
V
S
S
V
D
S
A
F
S
Chimpanzee
Pan troglodytes
XP_001134659
786
86619
S377
G
K
R
L
S
G
V
S
S
V
D
S
A
F
S
Rhesus Macaque
Macaca mulatta
XP_001107026
786
86655
S377
G
K
R
L
S
G
V
S
S
V
D
S
A
F
S
Dog
Lupus familis
XP_544897
826
90932
S417
G
K
R
L
S
G
V
S
S
V
D
S
A
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERK0
786
86594
S377
G
K
R
L
S
G
V
S
S
V
D
S
A
F
S
Rat
Rattus norvegicus
P0C8E4
606
67182
M240
G
G
P
A
F
R
I
M
W
A
V
H
N
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511321
791
87316
S377
G
K
R
L
S
G
V
S
S
V
D
S
A
F
S
Chicken
Gallus gallus
XP_416738
789
87316
R392
S
L
S
L
S
F
E
R
E
S
S
G
N
D
I
Frog
Xenopus laevis
NP_001080415
720
79835
G354
G
I
S
Q
T
M
E
G
P
G
C
L
S
H
S
Zebra Danio
Brachydanio rerio
Q502K3
1071
114412
L530
S
F
L
C
V
E
H
L
L
D
N
G
A
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180763
1378
147477
A498
L
T
P
L
H
L
A
A
Q
N
G
H
P
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
92.6
83.2
N.A.
84.9
23
N.A.
77.5
72.1
61.6
22
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
93.9
93.5
88.3
N.A.
89.3
38.9
N.A.
85.6
83.7
72.9
35.8
N.A.
N.A.
N.A.
N.A.
34.9
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
13.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
13.3
26.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
10
0
10
0
0
64
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
55
0
0
19
0
% D
% Glu:
0
0
0
0
0
10
19
0
10
0
0
0
0
10
0
% E
% Phe:
0
10
0
0
10
10
0
0
0
0
0
0
0
55
0
% F
% Gly:
73
10
0
0
0
55
0
10
0
10
10
19
0
10
0
% G
% His:
0
0
0
0
10
0
10
0
0
0
0
19
0
10
0
% H
% Ile:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
10
% I
% Lys:
0
55
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
10
73
0
10
0
10
10
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
10
0
19
0
0
% N
% Pro:
0
0
19
0
0
0
0
0
10
0
0
0
10
0
10
% P
% Gln:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
55
0
0
10
0
10
0
0
0
0
0
0
0
% R
% Ser:
19
0
19
0
64
0
0
55
55
10
10
55
10
0
64
% S
% Thr:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
10
0
55
0
0
55
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _